MKC8866
CAS No. 1338934-59-0
MKC8866 ( —— )
产品货号. M23496 CAS No. 1338934-59-0
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1596 | 有现货 |
|
10MG | ¥2592 | 有现货 |
|
25MG | ¥4358 | 有现货 |
|
50MG | ¥6310 | 有现货 |
|
100MG | ¥8829 | 有现货 |
|
500MG | ¥17658 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称MKC8866
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
-
产品描述MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体IRE1 RNase
-
研究领域——
-
适应症——
化学信息
-
CAS Number1338934-59-0
-
分子量361.4
-
分子式C18H19NO7
-
纯度>98% (HPLC)
-
溶解度DMSO:16.67 mg/mL (46.13 mM; Need ultrasonic)
-
SMILESO=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Sheng X, et al. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nat Commun. 2019 Jan 24;10(1):323.
产品手册
关联产品
-
Calycosin
Calycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.
-
GW-870086
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.