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MKC8866

CAS No. 1338934-59-0

MKC8866 ( —— )

产品货号. M23496 CAS No. 1338934-59-0

MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1596 有现货
10MG ¥2592 有现货
25MG ¥4358 有现货
50MG ¥6310 有现货
100MG ¥8829 有现货
500MG ¥17658 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    MKC8866
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
  • 产品描述
    MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    IRE1 RNase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1338934-59-0
  • 分子量
    361.4
  • 分子式
    C18H19NO7
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:16.67 mg/mL (46.13 mM; Need ultrasonic)
  • SMILES
    O=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Sheng X, et al. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nat Commun. 2019 Jan 24;10(1):323.
产品手册
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