MHI-148

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

MHI-148 是一种近红外七甲氨酸菁染料，具有肿瘤靶向性，可用于癌症检测、诊断和研究。MHI-148 可以立即被肿瘤细胞的溶酶体和线粒体吸收并积累，但在正常细胞的溶酶体和线粒体中不会。

MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells.

MHI-148 (10 μM, 1 h)?is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties. MHI-148 (0-1.5 μM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells.

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Others

Other Targets

Others

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172971-76-5

764.23

C42H52BrClN2O4

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 20.83 mg/mL (27.26 mM; 超声助溶 )

[Br-].O=C(O)CCCCCN1C=2C=CC=CC2C(C1=CC=C3C(Cl)=C(C=CC4=[N+](C=5C=CC=CC5C4(C)C)CCCCCC(=O)O)CCC3)(C)C

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(-20℃)

With Ice Pack

≥ 2 years