MD2-IN-1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 μM for the recombinant human MD2 (rhMD2).

MDK7229, also known as MD2-IN-1 is a MD2 (Myeloid differentiation protein 2) inhibitor. MDK7229 has CAS#111797-22-9. For easy communication, we use its last 4 digit of CAS for name. MDK7229 locked the LPS-induced activation of TLR4/MD2 -downstream pro-inflammatory MAPKs/NF-κB signaling pathways. In a rat model with ALI induced by intracheal LPS instillation, administration MDK7229 exhibited significant protective effect against ALI, accompanied by the inhibition of TLR4/MD2 complex formation in lung tissues.

MD2-IN-1; MDK7229; MDK 7229; MDK 7229.

Others

Other Targets

Myeloid differentiation protein 2(MD2)

Inflammation/Immunology

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111797-22-9

358.39

C20H22O6

98%

DMSO : 50 mg/mL 139.51 mM; H2O : < 0.1 mg/mL

COc1ccc(cc1OC)C(=O)\C=C\c1cc(OC)c(OC)c(OC)c1

(E)-1-(3,4-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

(-20℃)

With Ice Pack

≥ 2 years