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MCP110
CAS No. 521310-51-0
MCP110 ( MCP 110 )
产品货号. M14832 CAS No. 521310-51-0
MCP110 是一种有效的 Ras/Raf-1 相互作用抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1320 | 有现货 |
|
| 10MG | ￥2325 | 有现货 |
|
| 25MG | ￥4139 | 有现货 |
|
| 50MG | ￥6010 | 有现货 |
|
| 100MG | ￥7995 | 有现货 |
|
| 500MG | ￥16038 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MCP110
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MCP110 是一种有效的 Ras/Raf-1 相互作用抑制剂。
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产品描述MCP110 is a potent Ras/Raf-1 interaction inhibitor; inhibits Ras-induced Raf-1 activation in human embryonic kidney 293 cells, Raf-1 and MAPK1 activities in HT1080 fibrosarcoma cells, and EGF-induced Raf-1 activation in A549 lung carcinoma cells; inhibits anchorage-independent growth of A549 and PANC-1 cells harboring K-ras mutation; causes G1 enrichment of A549 cells with the decrease of cyclin D level; inhibits the growth of LXFA 629 lung and SW620 colon carcinoma cells in xenograft models.
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体外实验——
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体内实验——
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同义词MCP 110
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通路MAPK/ERK Signaling
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靶点Raf
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受体Raf
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研究领域——
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适应症——
化学信息
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CAS Number521310-51-0
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分子量508.662
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分子式C33H36N2O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (491.50 mM)
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SMILESCOC(C=C(CN(C(CCCCC1=CC=CC=C1)=O)CCC2=CC=CC=N2)C=C3)=C3OCC4=CC=CC=C4
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化学全称N-[[3-Methoxy-4-(phenylmethoxy)phenyl]methyl]-N-[2-(2-pyridinyl)ethyl]benzenepentanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kato-Stankiewicz J, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14398-403.
2. Skobeleva N, et al. Mol Cancer Ther. 2007 Mar;6(3):898-906.
3. González-Pérez V, et al. J Mol Signal. 2010 Feb 23;5:2.
