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MBCQ

CAS No. 150450-53-6

MBCQ ( —— )

产品货号. M22973 CAS No. 150450-53-6

MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥340 有现货
5MG ¥551 有现货
10MG ¥988 有现货
25MG ¥2001 有现货
50MG ¥3313 有现货
100MG ¥4779 有现货
500MG ¥10287 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    MBCQ
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
  • 产品描述
    MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
  • 同义词
    ——
  • 通路
    Angiogenesis
  • 靶点
    PDE
  • 受体
    PDE5
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    150450-53-6
  • 分子量
    313.74
  • 分子式
    C16H12ClN3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ClC1=CC2=C(N=CN=C2NCC3=CC=C(OCO4)C4=C3)C=C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Macpherson J D , Gillespie T D , Dunkerley H A , et al. Inhibition of Phosphodiesterase 5 Selectively Reverses Nitrate Tolerance in the Venous Circulation[J]. Journal of Pharmacology & Experimental Therapeutics, 2006, 317(1):188.
产品手册
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