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M4284
CAS No. 1373346-85-0
M4284 ( M-4284;M 4284 )
产品货号. M11539 CAS No. 1373346-85-0
M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2292 | 有现货 |
|
| 10MG | ￥3686 | 有现货 |
|
| 25MG | ￥6099 | 有现货 |
|
| 50MG | ￥8586 | 有现货 |
|
| 100MG | ￥11583 | 有现货 |
|
| 500MG | ￥23166 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称M4284
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay.
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产品描述M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay; reduces intestinal colonization of genetically diverse UPEC isolates, while simultaneously treating UTI, without notably disrupting the structural configuration of the gut microbiota; reduces UTI89 levels in the gut and urinary tracts of mice.
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同义词M-4284;M 4284
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Infection
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适应症——
化学信息
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CAS Number1373346-85-0
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分子量460.48
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分子式C23H28N2O8
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=C(C=CC(=C1)C2=CC(=CC(=C2)C(=O)NC)C(=O)NC)OC3C(C(C(C(O3)CO)O)O)O
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化学全称N3,N5,3'-trimethyl-4'-(((3S,4R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[1,1'-biphenyl]-3,5-dicarboxamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Spaulding CN, et al. Nature. 2017 Jun 22;546(7659):528-532.
2. Jarvis C, et al. ChemMedChem. 2016 Feb 17;11(4):367-73.
3. Han Z, et al. J Med Chem. 2012 Apr 26;55(8):3945-59.
2. Jarvis C, et al. ChemMedChem. 2016 Feb 17;11(4):367-73.
3. Han Z, et al. J Med Chem. 2012 Apr 26;55(8):3945-59.
产品手册
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