L-别异亮氨酸是一种支链氨基酸，是L-异亮氨酸的立体异构体。它是人体血浆的常见成分（尽管含量较低）。 L-别异亮氨酸是异亮氨酸转氨作用的副产物。血浆L-别异亮氨酸源自体内L-异亮氨酸，可用于诊断枫糖浆尿病（MSUD），一种遗传性疾病。

Copper histidine inhibited Ctr1-mediated cellular uptake of oxaliplatin in vitro without altering oxaliplatin accumulation of platinum or neurotoxicity in DRG tissues in vivo. Copper histidine is administered orally for the treatment of Menkes disease.

Syringaresinol is a lignan extracted from the sap of Lobelia longifolia with anti-inflammatory activity. syringaresinol causes vasodilation and enhances NO production through phosphorylation and dimerization of endothelial NO synthase.