Antifreeze Polypeptide (AFP) (HPLC-6), Winter Flounder ( ——— )

产品货号. M42055 CAS No. 122604-16-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Antifreeze Polypeptide (AFP) (HPLC-6), Winter Flounder
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Antifreeze Polypeptide 6 (winter flounder) 是美洲拟鲽抗冻多肽的第 6 成分。 Antifreeze Polypeptide 6 (winter flounder) 通过阻止冰核的生长降低血浆凝固点。
产品描述

Antifreeze Polypeptide 6 (winter flounder) is the component 6 of the winter flounder's antifreeze polypeptides. Antifreeze Polypeptide 6 (winter flounder) lowers the plasma freezing point by arresting the growth of ice nuclei.
体外实验

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体内实验

Antifreeze Polypeptide 6 (winter flounder) inhibits the growth of ice crystals by hydrogen bonding of Thr, Asn, and Asp side chains in a specific pattern to the hexagonal bipyramidal planes of ice. This mode of binding is unidirectional, maximizing opportunities for packing of AFPs on the ice surface, and that ice crystal growth inhibition occurs by a two-step mechanism involving hydrogen bonding and hydrophobic interpeptide interactions.
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1. Wen D, et al. A model for binding of an antifreeze polypeptide to ice. Biophys J. 1992 Dec;63(6):1659-62.?

计算器

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