Caloxin 2A1 ( ——— )

产品货号. M41851 CAS No. 350670-85-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Caloxin 2A1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Caloxin 2A1 是一种细胞外质膜 Ca2+-ATPase (PMCA) 肽抑制剂。Caloxin 2A1 不影响基础 Mg2+-ATPase 或 Na+-K+-ATPase。
产品描述

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase.
体外实验

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体内实验

Caloxin 2A1 inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate.Caloxin 2A1 increases airway smooth muscle cells (ASMCs) apoptosis.
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1. J Chaudhary, et al. Caloxin: a novel plasma membrane Ca2+ pump inhibitor. Am J Physiol Cell Physiol. 2001 Apr;280(4):C1027-30.?

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