5-O-Coumaroylquinic acid has a considerable inhibitory effect on PTP1B.5-O-Coumaroylquinic acid( 3-O-Coumaroylquinic acid) shows a significant concentration-dependent inhibitory effect on α-glucosidase, so it has anti-hyperglycemic effect.5-O-Coumaroylquinic acid(3-O-Coumaroylquinine acid) enhances glucose uptake and inhibits PTP1B in vitro.

[Hyp3]-Bradykinin 是一种天然存在的肽激素，是一种缓激肽受体 (bradykinin receptor) 激动剂。[Hyp3]-Bradykinin 与 B2-缓激肽受体相互作用并刺激人成纤维细胞中肌醇磷酸的产生。

COH34 analog 1，一种代谢产物，是 COH34 氧化类似物。COH34 是一种有效的 poly(ADP-ribose) glycohydrolase (PARG) 抑制剂。