Hyocholic Acid 是一种最早在猪体内发现的胆汁酸。Hyocholic Acid 也可以在胆汁淤积患者的尿液样本中发现。Hyocholic Acid 通过激活 TGR5 和抑制 FXR 促进肠内分泌细胞 GLP-1 分泌。Hyocholic Acid 可抵抗 2 型糖尿病。

Retene (NSC-26317) is widely present in recent and ancient sediments, and compounds can be extracted from fir forest soils, humic coals, terrestrial petroleum hydrocarbon source rocks, and deep-sea sediments.Retene is produced by dehydrogenation of pine acids during petrogenesis.

TPPU 是人和小鼠 sEH 的有效抑制剂（IC50 分别为 3.7 和 2.8 nM）。