Neuropeptide Y (18-36)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Neuropeptide Y (18-36) (porcine) 是一种竞争性神经肽 Y (NPY) 心脏受体拮抗剂。Neuropeptide Y (18-36) (porcine) 以浓度依赖性方式抑制 I-NPY 与心室膜的结合，IC50 值为 158 nM，Ki 值为 140 nM。Neuropeptide Y (18-36) (porcine) 可用于充血性心力衰竭的研究。

Neuropeptide Y (18-36) (porcine) is a competitive neuropeptide Y (NPY) cardiac receptor antagonist. Neuropeptide Y (18-36) (porcine) inhibits the binding of I-NPY to cardiac ventricular membranes in a concentration-dependent manner with an IC50 value of 158 nM and an Ki value of 140 nM. Neuropeptide Y (18-36) (porcine) can be used for the research of congestive heart failure.

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Neuropeptide Y (18-36) (porcine) inhibits the binding of I-NPY to rat cardiac ventricular membranes in a concentration-dependent manner with an IC50 value of 158 nM and an Ki value of 140 nM.Neuropeptide Y (18-36) (porcine) (1 μM) shifts the inhibitory adenylate cyclase activity dose-response curve of NPY to the right in a parallel fashion.Neuropeptide Y (18-36) (porcine) (1 μM) completely abolishes the effect of NPY (10 nM) that alone caused 80% of the maximum inhibition of adenylate cyclase activity.

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Others

Other Targets

IC50: 158 nM (I-NPY); Ki: 140 nM (I-NPY)

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114495-97-5

3000.5

C134H207N41O36S

>98% (HPLC)

DMSO : ≥ 100 mg/mL (40.70 mM; )

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(-20℃)

With Ice Pack

≥ 2 years