Osteocalcin (1-49) (human)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Osteocalcin (1-49) (human) 是一种依赖维生素 K 的骨特异性蛋白。Osteocalcin (1-49) (human) 对骨重塑表面常见的几种细胞类型具有趋化作用。

Osteocalcin (human) is a vitamin K-dependent bone specific protein. Osteocalcin (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces.

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Up to 20% of all non-collagenous protein in human bone consists of Osteocalcin. Only minor amounts of Osteocalcin are secreted into the blood circulation where it can be measured by immunochemical methods.Osteocalcin in serum is supposedly derived from newly synthesized bone, and the amount of this protein in serum may be a very specific marker for bone formation rate.Osteocalcin (1 nM-1 μM) is chemotactic for breast cancer cells and osteoblast-like osteogenic sarcoma cells as well as monocytes, and causes their unidirectional migration. Osteocalcin peptide contains 49 amino acids, with subsequent breakdown to fragments 1–19, 20–49, 20–43, 1–43, and 44–49 in the liver, kidney, and serum.

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Others

Other Targets

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136461-80-8

5925.6

C269H379N68O81S2

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years