Exendin-4 (3-39) ( ——— )

产品货号. M39924 CAS No. 196109-31-6

COA

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HNMR

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产品名称

Exendin-4 (3-39)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Exendin-4 (3-39) 是一种肽。Exendin-4 (3-39) 是 Exendin-4 的截断形式，缺少前两个氨基酸。Exendin-4 是一种有效的 GLP-1r 激动剂。Exendin-4 (3-39) 和 Exendin-4 可用于糖尿病和下丘脑-垂体-肾上腺 (HPA) 轴的研究。
产品描述

Exendin-4 (3-39) is a peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1 receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis.
体外实验

GLP-1 (i.p.; 5 μg/kg) increases circulating corticosterone and aldosterone levels.Animal Model:Rats Dosage:5 μg/kg Administration:Intraperitoneal injections Result:Increased circulating corticosterone levels in a time-dependent manner both in conscious and anaesthetized rats and also increased aldosterone levels.
体内实验

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通路

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Other Targets
受体

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研究领域

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适应症

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1. David Parkes, et al. Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1. (2001), 53(4), 260–267.

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