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Demethyleneberberine Chloride
CAS No. 16705-03-6
Demethyleneberberine Chloride ( 小檗碱杂质8；去亚甲基小檗碱盐酸盐 )
产品货号. M39506 CAS No. 16705-03-6
Demethyleneberberine chloride 是一种天然线粒体靶向抗氧化剂。Demethyleneberberine chloride 通过抑制 NF-κB 通路和调节 Th 细胞的平衡来减轻小鼠结肠炎并抑制炎症反应。Demethyleneberberine chloride 可作为 AMPK 激活剂，用于非酒精性脂肪性肝病 (NAFLD) 的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥420 | 有现货 |
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| 10MG | ￥820 | 有现货 |
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| 25MG | 获取报价 | 有现货 |
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| 50MG | 获取报价 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Demethyleneberberine Chloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Demethyleneberberine chloride 是一种天然线粒体靶向抗氧化剂。Demethyleneberberine chloride 通过抑制 NF-κB 通路和调节 Th 细胞的平衡来减轻小鼠结肠炎并抑制炎症反应。Demethyleneberberine chloride 可作为 AMPK 激活剂，用于非酒精性脂肪性肝病 (NAFLD) 的研究。
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产品描述Demethyleneberberine chloride is a natural mitochondria-targeted antioxidant. Demethyleneberberine chloride alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine chloride could serve as a AMPK activator for researching non-alcoholic fatty liver disease (NAFLD).
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体外实验———
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体内实验———
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同义词小檗碱杂质8；去亚甲基小檗碱盐酸盐
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通路Others
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靶点Other Targets
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受体———
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研究领域———
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适应症———
化学信息
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CAS Number16705-03-6
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分子量359.8
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分子式C19H18ClNO4
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纯度>98% (HPLC)
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溶解度DMSO : 2 mg/mL (5.56 mM; ultraphonic; )
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhang P, et al. Demethyleneberberine, a natural mitochondria-targeted antioxidant, inhibits mitochondrial dysfunction, oxidative stress, and steatosis in alcoholic liver disease mouse model. J Pharmacol Exp Ther. 2015 Jan;352(1):139-47.?
产品手册
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