KL-50

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions.

KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT.

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Others

Other Targets

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1161826-19-2

226.17

C7H7FN6O2

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years