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β-Amyrenonol
CAS No. 38242-02-3
β-Amyrenonol ( Β-香树脂酮醇 )
产品货号. M39376 CAS No. 38242-02-3
β-Amyrenonol (11-Oxo-β-amyrin) 是一种甘草根中的齐墩果型三萜，是甘草次酸的前体。β-Amyrenonol 具有抗增殖和抗炎活性，并可作为合成许多三萜类化合物的骨架。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3525 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称β-Amyrenonol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述β-Amyrenonol (11-Oxo-β-amyrin) 是一种甘草根中的齐墩果型三萜，是甘草次酸的前体。β-Amyrenonol 具有抗增殖和抗炎活性，并可作为合成许多三萜类化合物的骨架。
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产品描述β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids.
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体外实验———
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体内实验β-Amyrenonol (11-Oxo-β-amyrin) inhibits cell growth of HL60 cells with an IC50 value of 26.3 μM. β-Amyrenonol (11-Oxo-β-amyrin) (100 μM) significantly reduces lipopolysaccharide-induced TNFα release in THP-1 cells. CYP88D6 is characterized by in vitro enzymatic activity assays and shown to catalyze the sequential two-step oxidation of β-amyrin at C-11 to produce β-Amyrenonol (11-Oxo-β-amyrin). CYP88D6 coexpressed with β-amyrin synthase in yeast also catalyzed in vivo oxidation of β-amyrin to β-Amyrenonol.
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同义词Β-香树脂酮醇
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通路Others
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靶点Other Targets
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受体Others
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研究领域———
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适应症———
化学信息
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CAS Number38242-02-3
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分子量440.7
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分子式C30H48O2
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纯度>98% (HPLC)
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溶解度———
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. James Reed, et al. A Translational Synthetic Biology Platform for Rapid Access to Gram-Scale Quantities of Novel Drug-Like Molecules. Metab Eng. 2017 Jul;42:185-193.?
产品手册
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