Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

醋酸羟钴胺是一种可注射的天然维生素 B12 形式，具有良好的副作用，可用作治疗维生素 B12 缺乏症（包括恶性贫血）的膳食补充剂。

Cetaben 是一种不依赖于 PPARα 的过氧化物酶体增殖剂。 Cetaben是一种非纤维化降脂化合物，可有效降低胆固醇和甘油三酯浓度。