The herbs of Aloe vera L.

Trans-Petroselinic acid, the trans isomer of petroselinic acid and an isomer of oleic acid, is detected in the milk fat of cows, goats, and ewes, as well as human breast milk. In HepG2 cells, when treated with trans-petroselinic acid (100 μM), there is an increase in the cellular content of triacylglycerols and cholesterol esters. Additionally, it upregulates the transcription of genes associated with fatty acid synthesis (SREBP-1c, ACACA, FASN, SCD1) and cholesterol synthesis (HMGCR, HMGCS1, FDFT1, SREBP-2).

Deoxycholic acid (cholanoic acid) 是一种胆汁酸，肠道代谢副产物，可以激活 G 蛋白偶联胆汁酸受体 TGR5。