(R)-Ambrisentan-d3 是 (R)-Ambrisentan (A575873) 的氘化版本，它是非肽内皮素 ETA 受体拮抗剂 Ambrisentan (A575860) 的 R 异构体杂质。

ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).

HS271 是一种高效、口服活性的选择性 IRAK4 抑制剂，IC50 为 7.2 μM。 HS271 表现出卓越的酶活性和细胞活性，以及优异的药代动力学特性。