(S,S)-Secoisolariciresinol diglucoside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Secoisolariciresinol diglucoside ((S,S)-SDG) 是全麦亚麻籽中的主要木脂素，具有抗炎，抗氧化，抗诱变，抗微生物，抗肥胖，降血脂和神经保护作用。

Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects.

Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.Secoisolariciresinol diglucoside (1-50 μM; 24 h) attenuates human monocyte adhesion to and migration across human brain endothelial monolayers.

Secoisolariciresinol diglucoside (4 mg/mouse; a single p.o.) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.Animal Model:Hand feeding mice (10 weeks old, male) are injected with TNFα Dosage:4 mg/mouse Administration:P.o. 2 h before i.c. administration of TNFα Result:Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.

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Others

Antioxidant

Antioxidant

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257930-74-8

686.7

C32H46O16

>98% (HPLC)

In Vitro:?H2O 中的溶解度 : ≥ 100 mg/mL (145.62 mM)

[C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

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(-20℃)

With Ice Pack

≥ 2 years