Zolbetuximab
CAS No. 1496553-00-4
Zolbetuximab ( —— )
产品货号. M37695 CAS No. 1496553-00-4
Zolbetuximab (IMAB362) 是一种靶向 Claudin-18.2 的单克隆抗体。Zolbetuximab 通过免疫效应机制介导对 Claudin-18.2 阳性细胞的特异性杀伤。Zolbetuximab 可用于胃肠道腺癌和胰腺肿瘤的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥5216 | 有现货 |
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| 10MG | ¥7106 | 有现货 |
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| 25MG | ¥10137 | 有现货 |
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| 50MG | ¥13764 | 有现货 |
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| 100MG | ¥17820 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Zolbetuximab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Zolbetuximab (IMAB362) 是一种靶向 Claudin-18.2 的单克隆抗体。Zolbetuximab 通过免疫效应机制介导对 Claudin-18.2 阳性细胞的特异性杀伤。Zolbetuximab 可用于胃肠道腺癌和胰腺肿瘤的研究。
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产品描述Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors.
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体外实验——
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体内实验Animal Model:mouse BxPC-3-CLDN18.2, MIA PaCa-2-CLDN18.2 xenograft model Dosage:200 μg alone or with 50 mg/kg Gemcitabine Administration:i.v.; i.p. (Gemcitabine)Result:Inhibited tumor growth in two models, and prevented lung metastasis formation.Prolonged survival time, and lowered fractions of CLDN18.2+ cells in MIA PaCa-2-CLDN18.2 xenograft.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1496553-00-4
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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CGRP II, rat (TFA) (...
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
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Zoliprofen
Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat paw oedema, as well as anti-rat serum-induced fracture or dorsal skin oedema. Zoliprofen is 20 times more effective than ibuprofen and fenoprofen against collagen- or arachidonic acid-induced platelet aggregation in rats and rabbits. Zoliprofen was 20 times more effective than ibuprofen and fenoprofen in inhibiting endotoxin-induced diarrhoea in mice and arachidonic acid-induced acute mortality in rabbits.
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Dehydrodiisoeugenol
脱氢二异丁香酚抑制 LPS 刺激的 RAW264.7 小鼠巨噬细胞中 COX-2 的表达。
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