GSK778 hydrochloride ( —— )

产品货号. M37654 CAS No. 2863657-79-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

GSK778 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

GSK778 hydrochloride hydrochloride is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 hydrochloride hydrochloride phenocopies the effects of pan-BET inhibitors in cancer models.
产品描述

GSK778 hydrochloride hydrochloride is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 hydrochloride hydrochloride phenocopies the effects of pan-BET inhibitors in cancer models.
体外实验

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体内实验

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同义词

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通路

Chromatin/Epigenetic
靶点

Epigenetic Reader Domain
受体

Epigenetic Reader Domain
研究领域

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适应症

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CAS Number

2863657-79-6
分子量

548.08
分子式

C30H34ClN5O3
纯度

>98% (HPLC)
溶解度

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SMILES

C[C@@H](N1C(COC)=NC2=C1C3=CC(OC[C@@H]4CNCC4)=C(C5=C(C)ON=C5C)C=C3N=C2)C6=CC=CC=C6.[H]Cl
化学全称

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计算器

产品手册

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