Manool
CAS No. 596-85-0
Manool ( —— )
产品货号. M37189 CAS No. 596-85-0
Manool 是Salvia officinalis中的二萜。Manool 在癌细胞中诱导选择性的细胞毒性。Manool 使癌细胞停滞在细胞周期的 G(2)/M 期。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥331 | 有现货 |
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| 5MG | ¥540 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Manool
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Manool 是Salvia officinalis中的二萜。Manool 在癌细胞中诱导选择性的细胞毒性。Manool 使癌细胞停滞在细胞周期的 G(2)/M 期。
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产品描述Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle.
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体外实验Manool exhibits higher cytotoxic activity against HeLa (IC50=6.7 μg/mL) and U343 (IC50=6.7 μg/mL) cells.Manool exhibits a protective effect against chromosome damage induced by MMS in HepG2 cells.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number596-85-0
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分子量290.48
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分子式C20H34O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (344.26 mM; 超声助溶 )
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SMILESC[C@@]12[C@](C(C)(C)CCC1)(CCC(=C)[C@@H]2CC[C@@](C=C)(C)O)[H]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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9-(2,2-Dicyanovinyl)...
DCVJ (9-(2,2-Dicyanovinyl)julolidine) 是一种分子转子和独特的荧光染料,与微管蛋白和肌动蛋白结合,聚合后荧光强度显著增加。DCVJ 还与磷脂双层结合并增加其荧光强度。DCVJ 可以检测肥大细胞脱颗粒的动力学过程。
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β-Amyloid (7-22)
β-Amyloid (7-22)
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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