Atacicept
CAS No. 845264-92-8
Atacicept ( —— )
产品货号. M37167 CAS No. 845264-92-8
Atacicept (TACI-Ig) 是一种重组融合蛋白,包含 TACI 受体的细胞外配体结合部分和人 IgG 的 Fc 部分。Atacicept 通过结合 B 淋巴细胞刺激剂和增殖诱导配体抑制 B 细胞刺激。Atacicept 可用于 B 细胞自身免疫性疾病的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥10735 | 有现货 |
|
| 10MG | ¥14535 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Atacicept
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Atacicept (TACI-Ig) 是一种重组融合蛋白,包含 TACI 受体的细胞外配体结合部分和人 IgG 的 Fc 部分。Atacicept 通过结合 B 淋巴细胞刺激剂和增殖诱导配体抑制 B 细胞刺激。Atacicept 可用于 B 细胞自身免疫性疾病的研究。
-
产品描述Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease.
-
体外实验——
-
体内实验Atacicept (TACI-Ig; 100 μg; i.p.; three times of week for 14 days; BALB/c mice) reduces mature B-cell counts and serum antibody levels in normal mice.Atacicept (TACI-Ig) inhibits the progression of disease and autoantibody titers in a mouse model of collagen-induced arthritis (CIA).Animal Model:Male DBA/1 mice with CIA modelsDosage:100 μg Administration:intraperitoneal injection; three times of week for 21 days Result:Increased serum titers of anti-collagen Abs and few overt signs of disease.Animal Model:BALB/c mice Dosage:100 μg Administration:intraperitoneal injection; three times of week for 14 days Result:Reduced mature B cell populations but had little effect on other cell lineages.Blocked the development of B cells at the transition from T1 to T2 and the development of MZ B cells in the spleen.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number845264-92-8
-
分子量
-
分子式——
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Gross JA, et, al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity. 2001 Aug;15(2):289-302.??
产品手册
关联产品
-
Gastrin-Releasing Pe...
Gastrin-releasing peptide is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate the G cells of the stomach release GRP, which stimulates the G cells to release gastrin.
-
Eburnalritardo
Vinburnine(或 eburnamonine、Vincamone)是一种血管扩张剂。 Vincamone 是一种长春花生物碱,也是长春胺的代谢产物。
-
CY5
CY5 是一种 CY 染料。CY 为花菁 (Cyanine) 的缩写,是由奇数个甲基单位连接的两个氮原子组成的化合物。菁类化合物具有波长长、吸收和发射可调、消光系数高、水溶性好、合成相对简单等特点。CY 系类染料常被用于蛋白,抗体以及小分子化合物的标记,对于蛋白抗体的标记,可以通过简单的混合反应来完成结合,以下我们介绍了蛋白抗体标记的标记方法,具有一定的参考意义。
021-51111890
购物车()
sales@molnova.cn

