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GPX4-IN-5
CAS No. 2922824-09-5
GPX4-IN-5 ( —— )
产品货号. M37105 CAS No. 2922824-09-5
GPX4-IN-5 (Compound C18) 是一种 GPX4 共价抑制剂，IC50 值为 0.12 μM。GPX4-IN-5 (Compound C18) 可诱导铁死亡，用于三阴性乳腺癌 (TNBC) 的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1473 | 有现货 |
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| 10MG | ￥2309 | 有现货 |
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| 25MG | ￥3692 | 有现货 |
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| 50MG | ￥5385 | 有现货 |
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| 100MG | ￥7038 | 有现货 |
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| 200MG | ￥9450 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1216 | 有现货 |
|
生物学信息
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产品名称GPX4-IN-5
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GPX4-IN-5 (Compound C18) 是一种 GPX4 共价抑制剂，IC50 值为 0.12 μM。GPX4-IN-5 (Compound C18) 可诱导铁死亡，用于三阴性乳腺癌 (TNBC) 的研究。
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产品描述GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM.GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) .
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体GPX
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研究领域——
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适应症——
化学信息
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CAS Number2922824-09-5
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分子量381.78
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分子式C18H17ClFNO5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (261.93 mM; 超声助溶 )
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SMILESO=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.
产品手册
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