Rosmantuzumab
CAS No. 1684393-04-1
Rosmantuzumab ( —— )
产品货号. M37100 CAS No. 1684393-04-1
Rosmantuzumab (OMP-131R10) 是一种抗 R-spondin 3 (RSPO3) 人源化单克隆抗体。Rosmantuzumab 可用于晚期复发难治性实体瘤的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥5216 | 有现货 |
|
| 10MG | ¥7106 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Rosmantuzumab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Rosmantuzumab (OMP-131R10) 是一种抗 R-spondin 3 (RSPO3) 人源化单克隆抗体。Rosmantuzumab 可用于晚期复发难治性实体瘤的研究。
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产品描述Rosmantuzumab (OMP-131R10) is an anti-R-spondin 3 (RSPO3) humanized monoclonal antibody. Rosmantuzumab can be used for the research of advanced telapsed and refractory solid tumors.
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体外实验——
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体内实验Animal Model:Male C57B1/6J CCl4 liver fibrosis mouse models Dosage:25 mg/kg Administration:Intraperitoneal injection; 25 mg/kg, once a week for 4 weeks Result:Significantly decreased collagen I and collagen III mRNAs, and inhibits β-catenin cytoplasmic and nuclear translocation.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1684393-04-1
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhang M, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. PLoS One. 2020 Mar 11;15(3):e0229445.?
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