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Feeblin
CAS No. 689270-18-6
Feeblin ( —— )
产品货号. M37085 CAS No. 689270-18-6
IRF5-IN-1 (compound C5) 是一种 IRF5 通路特异性抑制剂。IRF5-IN-1 显着减少 IRF5 核转位，而不影响 NF-κB p65 的激活。IRF5-IN-1 通过 SLC15A4 起作用，选择性抑制细胞中 TLR7/8 诱导的 IRF5 反应。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥825 | 有现货 |
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| 10MG | ￥1311 | 有现货 |
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| 25MG | ￥2623 | 有现货 |
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| 50MG | ￥4241 | 有现货 |
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| 100MG | ￥5751 | 有现货 |
|
| 200MG | ￥7758 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥909 | 有现货 |
|
生物学信息
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产品名称Feeblin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述IRF5-IN-1 (compound C5) 是一种 IRF5 通路特异性抑制剂。IRF5-IN-1 显着减少 IRF5 核转位，而不影响 NF-κB p65 的激活。IRF5-IN-1 通过 SLC15A4 起作用，选择性抑制细胞中 TLR7/8 诱导的 IRF5 反应。
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产品描述IRF5-IN-1 (compound C5) is an IRF5 pathway-specific inhibitor. IRF5-IN-1 significantly reduces IRF5 nuclear translocation without affecting the activation of NF-κB p65. IRF5-IN-1 acts through SLC15A4 to selectively inhibit TLR7/8-induced IRF5 responses in cells.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number689270-18-6
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分子量431.57
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分子式C27H33N3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 50 mg/mL (115.86 mM; 超声助溶 (<80°C)
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SMILESO=C(NCCCN1CCCCC1C)C2=CC(=NC=3C=CC=CC32)C=4C=CC(OCC)=CC4
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Andras Boeszoermenyi, et al. A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. Nat Commun. 2023 Oct 20;14(1):6626.?
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