Tubulin polymerization-IN-47
CAS No. 2834087-62-4
Tubulin polymerization-IN-47 ( —— )
产品货号. M37020 CAS No. 2834087-62-4
Tubulinpolymerization-IN-47 (Compound 4h) 是一种 tubulin 聚合抑制剂和有丝分裂抑制剂。Tubulinpolymerization-IN-47 抑制神经母细胞瘤癌细胞增殖,对 Chp-134 和 Kelly 细胞系的IC50 分别为 7 和 12 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥525 | 有现货 |
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| 10MG | ¥858 | 有现货 |
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| 25MG | ¥1665 | 有现货 |
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| 50MG | ¥2325 | 有现货 |
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| 100MG | ¥3105 | 有现货 |
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| 200MG | ¥4077 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Tubulin polymerization-IN-47
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Tubulinpolymerization-IN-47 (Compound 4h) 是一种 tubulin 聚合抑制剂和有丝分裂抑制剂。Tubulinpolymerization-IN-47 抑制神经母细胞瘤癌细胞增殖,对 Chp-134 和 Kelly 细胞系的IC50 分别为 7 和 12 nM。
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产品描述Tubulin polymerization-IN-47 (Compound 4h) is a tubulin polymerization inhibitor and mitotic inhibitor. Tubulin polymerization-IN-47 inhibits neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell line.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Microtubule Associated
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研究领域——
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适应症——
化学信息
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CAS Number2834087-62-4
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分子量375.42
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分子式C22H21N3O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 125 mg/mL (332.96 mM; 超声助溶 (<60°C)
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SMILESO(C)C=1C=C(C=2C=3N(C=C(N3)C4=CC=C(C)C=C4)C=CN2)C=C(OC)C1OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Trans-Petroselinic acid, the trans isomer of petroselinic acid and an isomer of oleic acid, is detected in the milk fat of cows, goats, and ewes, as well as human breast milk. In HepG2 cells, when treated with trans-petroselinic acid (100 μM), there is an increase in the cellular content of triacylglycerols and cholesterol esters. Additionally, it upregulates the transcription of genes associated with fatty acid synthesis (SREBP-1c, ACACA, FASN, SCD1) and cholesterol synthesis (HMGCR, HMGCS1, FDFT1, SREBP-2).
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3-Methoxytyramine
3-甲氧基酪胺是一种众所周知的 3-羟基酪胺/多巴胺的细胞外代谢物,是一种神经调节剂。
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