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Ontuxizumab
CAS No. 946415-62-9
Ontuxizumab ( —— )
产品货号. M36874 CAS No. 946415-62-9
Ontuxizumab (MORAb-004) 是一种具有抗肿瘤作用的 IgG1/κ 抗内皮素 (TEM-1 或 CD248) 的单克隆抗体。Ontuxizumab 可用于癌症的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥5567 | 有现货 |
|
| 10MG | ￥7496 | 有现货 |
|
| 25MG | ￥10881 | 有现货 |
|
| 50MG | ￥14694 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ontuxizumab
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ontuxizumab (MORAb-004) 是一种具有抗肿瘤作用的 IgG1/κ 抗内皮素 (TEM-1 或 CD248) 的单克隆抗体。Ontuxizumab 可用于癌症的研究。
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产品描述Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer.
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体外实验——
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体内实验Animal Model:Human CD248 knock-in miceDosage:50 mg/kg Administration:Intravenous injection via tail vein; 50 mg/kg, 5 doses daily for 5 consecutive days Result:Reduced tumor growth with a lower level of CD248 and α-SMA on neovasculature pericytes.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number946415-62-9
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Rybinski K, et al. Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature. Oncotarget. 2015 Sep 22;6(28):25429-40.?
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