20R-Ginsenoside Rg2是一种具有抗氧化和抗细胞凋亡作用的化合物。

Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. Also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Stimulates angiogenesis in HUVEC cells. Relaxes mouse aortic vessels. Functions as an anorexigenic hormone through activation of the AVP and CRH neurons in the PVN.

Mulberrin 是 OATP2B1 介导的 estrone-3-sulfate (E3S) 摄取的抑制剂 (IC50: 1.8 ±1.5 μM)。