Vilobelimab
CAS No. 2250440-41-4
Vilobelimab ( —— )
产品货号. M36783 CAS No. 2250440-41-4
Vilobelimab (CaCP-29, IFX-1) 是一种单克隆抗 C5a 抗体,过敏毒素 C5a 是一种促炎补体分裂产物,在介导器官功能障碍中起核心作用。Vilobelimab 可作为一种 C5a 抑制剂,抑制中性粒细胞活化、趋化性,减少炎症信号等,可用于败血症,COVID-19 等相关研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥5567 | 有现货 |
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| 10MG | ¥7496 | 有现货 |
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| 25MG | ¥10881 | 有现货 |
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| 50MG | ¥14694 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Vilobelimab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Vilobelimab (CaCP-29, IFX-1) 是一种单克隆抗 C5a 抗体,过敏毒素 C5a 是一种促炎补体分裂产物,在介导器官功能障碍中起核心作用。Vilobelimab 可作为一种 C5a 抑制剂,抑制中性粒细胞活化、趋化性,减少炎症信号等,可用于败血症,COVID-19 等相关研究。
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产品描述Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number2250440-41-4
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Michael Bauer, et al. Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study). Crit Care Explor. 2021 Nov 17;3(11):e0577.?
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