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ATP dimagnesium
CAS No. 74804-12-9
ATP dimagnesium ( —— )
产品货号. M36632 CAS No. 74804-12-9
ATP (Adenosine 5'-triphosphate) dimagnesium 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。ATP dimagnesium 是免疫和炎症中重要的内源性信号分子。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥269 | 有现货 |
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| 100MG | ￥372 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ATP dimagnesium
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ATP (Adenosine 5'-triphosphate) dimagnesium 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。ATP dimagnesium 是免疫和炎症中重要的内源性信号分子。
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产品描述ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation.
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体外实验ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.ATP promotes neutrophil chemotaxis in vitro.
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体内实验ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.Animal Model:Four-week-old Kunming mice (18-22 g)Dosage:50 mg/kg Administration: Intraperitoneal injection, before bacterial (E. coli) challenge Result:Protected mice from bacterial infection.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number74804-12-9
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分子量551.76
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分子式C10H12Mg2N5O13P3
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O 中的溶解度 : 250 mg/mL (453.10 mM; 超声助溶)
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SMILES[Mg++].[Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.?
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