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Basiliximab
CAS No. 179045-86-4
Basiliximab ( —— )
产品货号. M36560 CAS No. 179045-86-4
Basiliximab (CHI 621) 是一种重组嵌合鼠/人 IgG1 单克隆抗白细胞介素 2 受体 (interleukin-2 receptor) 抗体。Basiliximab 可用于肾移植研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥6897 | 有现货 |
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| 10MG | ￥9301 | 有现货 |
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| 25MG | ￥13485 | 有现货 |
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| 50MG | ￥18228 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Basiliximab
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Basiliximab (CHI 621) 是一种重组嵌合鼠/人 IgG1 单克隆抗白细胞介素 2 受体 (interleukin-2 receptor) 抗体。Basiliximab 可用于肾移植研究。
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产品描述Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.
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体外实验Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα.Basiliximab binds only to activated lymphocytes and macrophages/monocytes. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα.
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体内实验Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats.Animal Model:Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia Dosage:0.07 mg/rat Administration:IV infusion, once Result:Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
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同义词——
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通路Others
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靶点Other Targets
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受体Interleukin
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研究领域——
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适应症——
化学信息
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CAS Number179045-86-4
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. McKeage K, et al. Basiliximab: a review of its use as induction therapy in renal transplantation. BioDrugs. 2010 Feb 1;24(1):55-76.?
