(S)-HH2853 ( —— )

产品货号. M36496 CAS No. 2202678-05-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(S)-HH2853
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(S)-HH2853 (compound 200) 是一种 PYRIDINO 五元芳环化合物，一种有效的 EZH1/2 双重抑制剂，对 EZH2_Y641F 的 IC50 为 <100 nM。(S)-HH2853有潜力用于抗肿瘤或自身免疫性疾病的研究。
产品描述

(S)-HH2853 (compound 200), a PYRIDINO five membered aromatic ring compound, is a potent EZH1/2 dual inhibitor with an IC50 of <100 nM for EZH2_Y641F. (S)-HH2853 has the potential to be used in the research of anti-tumor or autoimmune diseases.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Histone Methyltransferase
研究领域

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适应症

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CAS Number

2202678-05-3
分子量

611.66
分子式

C31H36F3N7O3
纯度

>98% (HPLC)
溶解度

——
SMILES

[C@H](C)(C=1N2C(=C(C=C2)C3=CC=C(C)N=N3)C=C(C(NCC4=C(OC)C=C(C)NC4=O)=O)C1C)N5CCN(CC(F)(F)F)CC5
化学全称

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1. Xuxing Chen, et al. PYRIDINO five membered aromatic ring compounds, preparation method and application thereof. WO2018045971A1.

计算器

产品手册

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