Pinokalant

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Pinokalant 是一种广谱阳离子通道抑制剂。Pinokalant 显着减少皮质梗死体积。Pinokalant 改善缺血半影区的代谢和电生理状态。Pinokalant 可减少大鼠大脑中动脉闭塞后急性期磁共振图像上的病变大小。Pinokalant 具有研究脑卒中的潜力。

Pinokalant is a broad-spectrum and non-selectivecation channel inhibitor. Pinokalant significantly reduces cortical infarct volume. Pinokalant o improves the metabolic and electrophysiologic status of the ischemic penumbra. Pinokalant reduces lesion size on magnetic resonance images in the acute phase following middle cerebral artery occlusion in rats. Pinokalant has the potential for the research of stroke. Pinokalant also shows anti-SARS-CoV-2 activity.

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Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3.

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Membrane Transporter/Ion Channel

TRP/TRPV Channel

TRP/TRPV Channel | SARS-CoV

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149759-26-2

712.83

C41H48N2O9

>98% (HPLC)

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C(C(N(CCC1=C(OC)C(OC)=C(OC)C=C1)CCC2=C(OC)C(OC)=C(OC)C=C2)=O)(C=3C=4C(=CC(OC)=C(OC)C4)CCN3)C5=CC=CC=C5

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(-20℃)

With Ice Pack

≥ 2 years