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Berberine ursodeoxycholate

CAS No. 1868138-66-2

Berberine ursodeoxycholate ( —— )

产品货号. M36122 CAS No. 1868138-66-2

Berberine ursodeoxycholate (HTD1801) 是 Berberine 和 Ursodeoxycholic acid 的一种离子盐,是一种口服有效的降血脂剂 (hypolipidemic agent)。Berberine ursodeoxycholate 能显著降低肝脏脂肪含量。Berberine ursodeoxycholate 具有广泛的代谢活性。Berberine ursodeoxycholate 可用于高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病的研究。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥708 有现货
10MG ¥1131 有现货
25MG ¥2213 有现货
50MG ¥3553 有现货
100MG ¥4887 有现货
200MG ¥6678 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Berberine ursodeoxycholate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Berberine ursodeoxycholate (HTD1801) 是 Berberine 和 Ursodeoxycholic acid 的一种离子盐,是一种口服有效的降血脂剂 (hypolipidemic agent)。Berberine ursodeoxycholate 能显著降低肝脏脂肪含量。Berberine ursodeoxycholate 具有广泛的代谢活性。Berberine ursodeoxycholate 可用于高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病的研究。
  • 产品描述
    Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
  • 体外实验
    ——
  • 体内实验
    Berberine ursodeoxycholate shows significant reductions in HbA1c (hemoglobin A1c) levels, mean HbA1c levels decreases by 0.6%.Berberine ursodeoxycholate is ingested in the form of a salt and it is thought that the salt promptly dissociates within the gastrointestinal tract and that Berberine and Ursodeoxycholic acid are differentially absorbed.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1868138-66-2
  • 分子量
    217.69
  • 分子式
    C6H8CuN3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO 中的溶解度 : 5 mg/mL (6.87 mM; 超声助溶 (<60°C)
  • SMILES
    COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Harrison SA, et al. A phase 2, proof of concept, randomised controlled trial of berberine ursodeoxycholate in patients with presumed non-alcoholic steatohepatitis and type 2 diabetes. Nat Commun. 2021 Sep 17;12(1):5503.?
产品手册
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