Flavin adenine dinucleotide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Flavin adenine dinucleotide (FAD) 是一种氧化还原辅因子，蛋白质的辅基，在代谢过程中参与了几个重要的酶反应。

Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

Poly(Flavin adenine dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry.

Flavin adenine dinucleotide (2 mg/kg, i.v.) significantly cancels chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). Flavin adenine dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin adenine dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin adenine dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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146-14-5

785.55

C27H33N9O15P2

>98% (HPLC)

In Vitro:?H2O 中的溶解度 : 125 mg/mL (159.12 mM; 超声助溶)

C([C@@H]([C@@H]([C@@H](COP(OP(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=3C(N=C2)=C(N)N=CN3)(=O)O)(=O)O)O)O)O)N4C=5C(=NC=6C4=CC(C)=C(C)C6)C(=O)NC(=O)N5

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(-20℃)

With Ice Pack

≥ 2 years