Cuprizone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Cuprizone 是一种铜螯合剂，可与铜 (II) 形成深蓝色铜酮络合物。 铜酮反应可用于比色测试中是否存在痕量铜。Cuprizone 可用于诱导小鼠的一些精神分裂症样行为。Cuprizone 作用于铜酶，包括 SOD1、细胞色素氧化酶和 DβH，从而导致氧化应激并增加某些大脑区域如内侧前额叶皮层 (PFC) 的 DA 水平。

Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC).

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Others

Other Targets

Others

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370-81-0

278.35

C14H22N4O2

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 6.67 mg/mL (23.96 mM; 超声助溶 (<60°C)

O=C(NN=C1CCCCC1)C(=O)NN=C1CCCCC1

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(-20℃)

With Ice Pack

≥ 2 years