Anti-inflammatory agent 36

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Anti-inflammatory agent 36 是一种抗炎剂。Anti-inflammatory agent 36 抑制 LPS 诱导的巨噬细胞活化。

Anti-inflammatory agent 36 is an anti-inflammatory agent. Anti-inflammatory agent 36 inhibits LPS-induced macrophage activation.

Western Blot Analysis Cell Line:RAW 264.7 mouse macrophages Concentration:10 μM Incubation Time:0.5 h Result:Markedly inhibited P-P38 and P-ERK, indicating the suppression of MAPK signaling.

Animal Model:Acute lung injury mouse model Dosage:10 mg/kg Administration:i.p.Result:Reduced wet/dry weight ratio of the mice lungs.Reduced biomarkers of lymphocytes and macrophages.Suppresses TNF-α, IL-6, IL-1β, 7 VACM-1 and ICAM-1 level.

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Others

Other Targets

Immunology/Inflammation related

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2293951-01-4

453.48

C25H27NO7

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 25 mg/mL (55.13 mM; 超声助溶 (<60°C)

COc1cc(\C=C\C(=O)N2CCC\C(=C/c3cc(OC)c(OC)c(OC)c3)C2=O)ccc1O

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(-20℃)

With Ice Pack

≥ 2 years