PI-55

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PI-55 是特异性 cytokinin receptor 抑制剂。PI-55 在结构上与 6-benzylaminopurine (BAP) 相关，并被证明能竞争性地抑制 BAP 与拟南芥特异性受体 CRE1/AHK4 和 AHK3 的结合。PI-55 抑制细胞分裂素诱导吸器形成和寄生虫侵袭性增加。

PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness.

PI-55 at high concentrations (10 μM and 100 μM), which causes an incomplete blocking of early haustorial structure development, especially when cytokinin activity promotes it. PI-55 treatment also reduces the overall aggressiveness of P. ramosa when applied with BAP in comparison with BAP alone, suggesting that the signaling pathway leading to early haustorial structure formation involves histidine kinase receptors homologous to CRE1/AHK4 and AHK3.

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Others

Other Targets

Others

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1122579-42-3

255.28

C13H13N5O

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 25 mg/mL (97.93 mM; 超声助溶 (<60°C)

Cc1cccc(CNc2ncnc3[nH]cnc23)c1O

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(-20℃)

With Ice Pack

≥ 2 years