L-Azidohomoalanine hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

L-Azidohomoalanine hydrochloride 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。L-Azidohomoalanine (hydrochloride) 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。

L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-Azidohomoalanine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

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PROTACs

PROTAC

PROTAC Linker

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942518-29-8

180.59

C4H9ClN4O2

>98% (HPLC)

In Vitro:?H2O 中的溶解度 : 125 mg/mL (692.18 mM; 超声助溶)

Cl.N[C@@H](CCN=[N+]=[N-])C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years