6-Azido-hexylamine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

6-Azido-hexylamine是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。6-Azido-hexylamine 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Antibody Drug Conjugates (ADC)

ADCs Linker/Click Chemistry

ADC Linker

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349553-73-7

142.2022

C6H14N4

>98% (HPLC)

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NCCCCCCN=[N+]=[N-]

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(-20℃)

With Ice Pack

≥ 2 years