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N-Desmethyl Pimavanserin
CAS No. 639863-77-7
N-Desmethyl Pimavanserin ( —— )
产品货号. M34992 CAS No. 639863-77-7
N-Desmethyl Pimavanserin 是 Pimavanserin 的活性代谢物。Pimavanserin 是选择性的 5-HT2A 受体反向激动剂， pIC50 和 pKd 分别为 8.73 和 9.3。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1606 | 有现货 |
|
| 5MG | ￥2679 | 有现货 |
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| 10MG | ￥3772 | 有现货 |
|
| 25MG | ￥5980 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥2432 | 有现货 |
|
生物学信息
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产品名称N-Desmethyl Pimavanserin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述N-Desmethyl Pimavanserin 是 Pimavanserin 的活性代谢物。Pimavanserin 是选择性的 5-HT2A 受体反向激动剂， pIC50 和 pKd 分别为 8.73 和 9.3。
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产品描述N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
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体外实验The mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number639863-77-7
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分子量413.53
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分子式C24H32FN3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 125 mg/mL (302.28 mM; 超声助溶 (<60°C)
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SMILESCC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCNCC2)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Vanover KE, et al. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inver?
产品手册
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