Isolithocholic Acid

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Isolithocholic acid (β-Lithocholic acid) 是石胆酸的一种同分异构体。Isolithocholic acid 是一种胆酸，由 Lithocholic acid 或 Lithocholic acid 3α-sulfate 经微生物代谢形成。

Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.

Isolithocholic acid at 0.01 % does not inhibit spore germination and outgrowth of CF5 and M120, but it significantly inhibits at the higher concentration (0.1 %). Isolithocholic acid (0.00003 %) prevents growth of CD196, M68, CF5, 630, and BI9 and significant decreases strains CF5, BI9, M120, and 630 in toxin activity. Isolithocholic acid (0.0003 %) makes that all strains displays a significant decrease in toxin activity, except for R20291 and M120.

The levels of fecal Isolithocholic acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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1534-35-6

376.57

C24H40O3

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 28.57 mg/mL (75.87 mM; 超声助溶 )

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years