DA-6886 ( —— )

产品货号. M34220 CAS No. 1645260-76-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

DA-6886
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
产品描述

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
体外实验

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体内实验

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同义词

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通路

GPCR/G Protein
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

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适应症

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计算器

产品手册

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