Parathyroid Hormone (1-34), bovine
CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine ( —— )
产品货号. M33742 CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥1891 | 有现货 |
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| 10MG | ¥2831 | 有现货 |
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| 25MG | ¥4492 | 有现货 |
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| 50MG | ¥6222 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Parathyroid Hormone (1-34), bovine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。
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产品描述Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis.
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体外实验Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal.Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group.Cell Proliferation Assay Cell Line: MC3T3-E1 cells Concentration:0.1-100 ng/mL Incubation Time:2-20 days Result:Resulted a decrease of osteoblast proliferationin concentration-dependent manner.
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体内实验Parathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls.
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同义词——
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通路Endocrinology/Hormones
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靶点THR
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受体Thyroid hormone receptor(THR)
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研究领域——
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适应症——
化学信息
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CAS Number12583-68-5
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分子量4104.39
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分子式C183H288N54O50S2
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O 中的溶解度 : 50 mg/mL (12.17 mM; 超声助溶)
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84.?
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