Triclopyr

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Triclopyr 是一种叶面系统性除草剂和杀真菌剂，被广泛用于阔叶和木本植物的防治。Triclopyr 具有严重的毒性。

Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity.

Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells.Cell Cytotoxicity Assay Cell Line:Mouse neuroblastoma (N2a) cells Concentration:3 mM Incubation Time:48 hours Result:Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.

Pharmacokinetic Analysis Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) .Animal Model:3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey Dosage:0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey) Administration:Oral gavage (beagle dog); intravenous (rhesus monkey)Result:T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.

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Microbiology/Virology

Antifungal

Antifungal

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55335-06-3

256.47

C7H4Cl3NO3

>98% (HPLC)

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O=C(O)COC1=NC(Cl)=C(Cl)C=C1Cl

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(-20℃)

With Ice Pack

≥ 2 years