Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.

异戊酰甘氨酸 (IVG) 是一种酰基甘氨酸。酰基甘氨酸通常是脂肪酸的次要代谢物。然而，某些酰基甘氨酸的排泄在一些先天性代谢缺陷中会增加。在某些情况下，体液中这些代谢物的测量可用于诊断与线粒体脂肪酸β-氧化相关的疾病。

R112 是 Syk 激酶的 ATP 竞争性抑制剂。