Adrenochrome

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Adrenochrome (Adraxone) 是 Epinephrine 的氧化产物。Adrenochrome 是大鼠心脏中一种有效的冠状动脉收缩剂。Adrenochrome 可用于神经系统疾病研究。

Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research.

Adrenochrome decreases microsomal calcium binding, calcium uptake and Ca2+-stimulated Mg2+-dependent ATPase activities. The inhibitory effect of Adrenochrome on microsomal calcium uptake activity of the isolated membrane is independent of pH (6.0-8.0), calcium concentrations (10-200 μM), protein concentration (0.02-0.10 mg/mL), temperature (25-37 degrees C) and incubation time (2-30 min).

In isolated rat hearts, concentrations of Adrenochrome from 1 to 1000 ng/mL increases coronary pressure in a dose- and time-dependent manner. Furthermore, the degree of constriction by Adrenochrome is dependent on the CaCl2 concentration in the perfusion medium.

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Others

Antioxidant

Antioxidant

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54-06-8

179.17

C9H9NO3

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (558.13 mM; 超声助溶 )

OC1C=2C(N(C)C1)=CC(=O)C(=O)C2

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(-20℃)

With Ice Pack

≥ 2 years